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Moderne Bibliothek

2023

Albaugh, M. D., Owens, M. M., Juliano, A., Ottino-Gonzalez, J., Cupertino, R., Cao, Z., Mackey, S., Lepage, C., Rioux, P., Evans, A., Banaschewski, T., Bokde, A. L. W., Conrod, P., Desrivières, S., Flor, H., Grigis, A., Gowland, P., Heinz, A., Ittermann, B., … Garavan, H. (2023). Differential associations of adolescent versus young adult cannabis initiation with longitudinal brain change and behavior. Molecular Psychiatry. https://doi.org/10.1038/s41380-023-02148-2

Albaugh, M. D., Hudziak, J. J., Spechler, P. A., Chaarani, B., Lepage, C., Jeon, S., Rioux, P., Evans, A. C., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. L. P., Nees, F., Orfanos, D. P., … Garavan, H. (2023). Conduct problems are associated with accelerated thinning of emotion-related cortical regions in a community-based sample of adolescents. Psychiatry Research - Neuroimaging, 330. https://doi.org/10.1016/j.pscychresns.2023.111614

Bach P, Zaiser J, Zimmermann S, Gessner T, Hoffmann S, Gerhardt S, Berhe O, Bekier NK, Abel M, Radler P, Langejürgen J, Tost H, Lenz B, Vollstädt-Klein S, Stallkamp J, Kirschbaum C, Kiefer F. Stress-induced sensitization of insula activation predicts alcohol craving and alcohol use in alcohol use disorder. Biol Psychiatry. 2023 Sep 5:S0006-3223(23)01555-X. doi: 10.1016/j.biopsych.2023.08.024. Epub ahead of print. PMID: 37678541.

Baeuchl, C., Glöckner, F., Koch, C., Petzold, J., Schuck, N. W., Smolka, M. N., & Li, S. C. (2023). Dopamine differentially modulates medial temporal lobe activity and behavior during spatial navigation in young and older adults. NeuroImage, 273. https://doi.org/10.1016/j.neuroimage.2023.120099

Beck, A. (2023). Disentangling Brain Network Connectivity During Monetary and Drug-Related Reward Processing in Stimulant Use Disorder. In Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (Vol. 8, Issue 5). https://doi.org/10.1016/j.bpsc.2023.03.006

Beck A, Ebrahimi C, Rosenthal A, Charlet K, Heinz A (2023) The Dopamine System in Mediating Alcohol Effects in Humans. Curr Top Behav Neurosci Jan 28. doi: 10.1007/7854_2022_415. 

Berhe, O., Höflich, A., Moessnang, C., Reichert, M., Kremer, T., Gan, G., Ma, R., Braun, U., Reininghaus, U., Ebner-Priemer, U., Meyer-Lindenberg, A., & Tost, H. (2023). Reduced Real-life Affective Well-being and Amygdala Habituation in Unmedicated Community Individuals at Risk for Depression and Anxiety. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 8(1). https://doi.org/10.1016/j.bpsc.2022.06.009

Chen H, Belanger MJ, Garbusow M, Kuitunen-Paul S, Huys QJM, Heinz A, Rapp MA, Smolka MN (2023) Susceptibility to interference between Pavlovian and instrumental control predisposes risky alcohol use developmental trajectory from ages 18 to 24. Addict Biol 28(2):e13263. doi: 10.1111/adb.13263.

Chen, K., Schlagenhauf, F., Sebold, M., Kuitunen-Paul, S., Chen, H., Huys, Q. J. M., Heinz, A., Smolka, M. N., Zimmermann, U. S., & Garbusow, M. (2023). The Association of Non–Drug-Related Pavlovian-to-Instrumental Transfer Effect in Nucleus Accumbens With Relapse in Alcohol Dependence: A Replication. Biological Psychiatry, 93(6). https://doi.org/10.1016/j.biopsych.2022.09.017

Chen, K., Wüstenberg, T., Stiglbauer, V., El‐Ahmad, L., Rosenthal, A., Pelz, P., ... & Sebold, M. (2023). Distinct dynamic behavioural response to social exclusion in male patients with a history of alcohol dependence. Addiction Biology, 28(7), e13287. https://doi.org/10.1111/adb.13287

de Matos, K., Cury, C., Chougar, L., Strike, L. T., Rolland, T., Riche, M., Hemforth, L., Martin, A., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Paillère Martinot, M. L., … Couvy-Duchesne, B. (2023). Temporo-basal sulcal connections: a manual annotation protocol and an investigation of sexual dimorphism and heritability. Brain Structure and Function, 228(6). https://doi.org/10.1007/s00429-023-02663-6

Domanegg, K.; Sommer, W.H.; Meinhardt, M.W. Psychedelic Targeting of Metabotropic Glutamate Receptor 2 and Its Implications for the Treatment of Alcoholism. Cells 2023, 12, 963. https://doi.org/10.3390/cells12060963

Ebrahimi, C., Garbusow, M., Sebold, M., Chen, K., Smolka, M. N., Huys, Q. J. M., Zimmermann, U. S., Schlagenhauf, F., & Heinz, A. (2023). Elevated Amygdala Responses During De Novo Pavlovian Conditioning in Alcohol Use Disorder Are Associated With Pavlovian-to-Instrumental Transfer and Relapse Latency. Biological psychiatry global open science, 3(4), 803–813. https://doi.org/10.1016/j.bpsgos.2023.02.003

Endrass, T., & Weiss, F. (2023). Performance Monitoring: A Transdiagnostic Biomarker of Adaptive Behavior in Mental Disorders. In Biological Psychiatry (Vol. 93, Issue 11). https://doi.org/10.1016/j.biopsych.2023.03.007

Foo JC, Skorodumov I, Spanagel R, Meinhardt MW. Sex- and age-specific effects on the development of addiction and compulsive-like drinking in rats. Biol Sex Differ 14, 44 (2023).

Friske MM, Giannone F, Senger M, Seitz R, Hansson AC, Spanagel R (2023) Chronic alcohol intake regulates expression of SARS-CoV2 infection-relevant genes in an organ-specific manner. Alcohol Clin Exp Res 47(1):76-86. doi: 10.1111/acer.14981. 

Friske MM, Spanagel R (2023) Chronic alcohol consumption and COVID-19 infection risk: A narrative review. Alcohol Clin Exp Res doi:10.1111/acer.15041

Frölich, S., Esmeyer, M., Endrass, T., Smolka, M. N., & Kiebel, S. J. (2023). Interaction between habits as action sequences and goal-directed behavior under time pressure. Frontiers in Neuroscience, 16. https://doi.org/10.3389/fnins.2022.996957

Gerhardt S, Berhe O, Moessnang C, Horning M, Kiefer F, Tost H, Vollstädt-Klein S (2023) Lack of amygdala habituation to negative emotional faces in alcohol use disorder and the relation to adverse childhood experiences. Addict Biol 28(1):e13251. doi: 10.1111/adb.13251.

 

Gholamipourbarogh N, Ghin F, Mückschel M, Frings C, Stock AK, Beste C (2023) Evidence for independent representational contents in inhibitory control subprocesses associated with frontoparietal cortices. Hum Brain Mapp 44(3):1046-1061. doi: 10.1002/hbm.26135.

Golde, S., Gleich, T., Romund, L., Stippl, A., Pelz, P., Raufelder, D., . . . Beck, A. (2023). Adolescents’ neural reactivity to acute psychosocial stress: Dysfunctional regulation habits are linked to temporal gyrus response. Development and Psychopathology, 35(1), 332-344. doi:10.1017/S0954579421000572

 

Guldner, S., Sarvasmaa, A. S., Lemaître, H., Massicotte, J., Vulser, H., Miranda, R., Bezivin – Frère, P., Filippi, I., Penttilä, J., Banaschewski, T., Barker, G. J., Bokde, A. L., Bromberg, U., Büchel, C., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., … Martinot, J. L. (2023). Longitudinal associations between adolescent catch-up sleep, white-matter maturation and internalizing problems. Developmental Cognitive Neuroscience, 59. https://doi.org/10.1016/j.dcn.2022.101193

Hildebrandt MK, Schwarz K, Dieterich R, Endrass T. Dissociating the Link of Neural Correlates of Inhibition to the Degree of Substance Use and Substance-Related Problems: A Preregistered, Multimodal, Combined Cross-sectional and Longitudinal Study. Biol Psychiatry. 2023 Dec 1;94(11):898-905. doi: 10.1016/j.biopsych.2023.06.017. Epub 2023 Jun 24. PMID: 37356556.

Hoffmann S, Gerhardt S, Koopmann A, Bach P, Sommer WH, Kiefer F, Mazza M, Lenz B (2023) Body mass index interacts with sex to predict readmission in in-patients with alcohol use disorder. Addict Biol 28(1):e13239. doi: 10.1111/adb.13239.

Holz NE, Berhe O, Sacu S, Schwarz E, Tesarz J, Heim CM, Tost H (2023) Early Social Adversity, Altered Brain Functional Connectivity, and Mental Health. Biol Psychiatry 93(5):430-441. doi: 10.1016/j.biopsych.2022.10.019. 

Holz, N.E., Zabihi, M., Kia, S.M. et al. A stable and replicable neural signature of lifespan adversity in the adult brain. Nat Neurosci 26, 1603–1612 (2023). https://doi.org/10.1038/s41593-023-01410-8

Hornoiu, I. L., Lee, A. M., Tan, H., Nakovics, H., Bach, P., Mann, K., Kiefer, F., Sommer, W. H., & Vollstädt-Klein, S. (2023). The Role of Unawareness, Volition, and Neural Hyperconnectivity in Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 8(6). https://doi.org/10.1016/j.bpsc.2022.12.008

Isıklı, S., Bahtiyar, G., Zorlu, N., Düsmez, S., Bağcı, B., Bayrakcı, A., Heinz, A., & Sebold, M. (2023). Reduced sensitivity but intact motivation to monetary rewards and reversal learning in obesity. Addictive Behaviors, 140. https://doi.org/10.1016/j.addbeh.2022.107599

Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Sembritzki NK, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Lenz B, Schumann G, Kornhuber J, Müller CP (2023) Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males. Cereb Cortex 33(3):844-864. doi: 10.1093/cercor/bhac106.

Karl D, Wieland A, Shevchenko Y, Grundinger N, Machunze N, Gerhardt S, Flor H, Vollstädt-Klein S (2023) Using computer-based habit versus chess-based cognitive remediation training as add-on therapy to modify the imbalance between habitual behavior and cognitive control in tobacco use disorder: protocol of a randomized controlled, fMRI study. BMC Psychol 11(1):24. doi: 10.1186/s40359-023-01055-z.

Klingenberg, M., Stark, D., Eitel, F., Budding, C., Habes, M., & Ritter, K. (2023). Higher performance for women than men in MRI-based Alzheimer’s disease detection. Alzheimer’s Research and Therapy, 15(1). https://doi.org/10.1186/s13195-023-01225-6

Lenz B, Gerhardt S, Boroumand-Jazi R, Eichler A, Buchholz VN, Fasching PA, Kornhuber J, Banaschewski T, Flor H, Guldner S, Prignitz M, Nees F, IMAC-Mind Consortium . Sex-specific association between prenatal androgenization (second-to-fourth digit length ratio) and frontal brain volumes in adolescents. Eur Arch Psychiatry Clin Neurosci. 2022 Nov 30. [Epub ahead of print]

Lütt, A., Tsamitros, N., Wolbers, T., Rosenthal, A., Bröcker, A. L., Schöneck, R., ... & Gutwinski, S. (2023). An explorative single-arm clinical study to assess craving in patients with alcohol use disorder using Virtual Reality exposure (CRAVE)—study protocol. BMC psychiatry, 23(1), 839. https://doi.org/10.1186/s12888-023-05346-y

Marxen M, Graff JE, Riedel P, Smolka MN (2023) Observing cognitive processes in time through functional MRI model comparison. Hum Brain Mapp 44(4):1359-1370. doi: 10.1002/hbm.

Meinhardt MW, Sommer WH (2023) Schrooms against booze: Potential of mycotherapy for the treatment of AUD. Neuropsychopharmacology 48(1):211-212. doi: 10.1038/s41386-022-01446-7.

Mikolas, P., Marxen, M., Riedel, P., Bröckel, K., Martini, J., Huth, F., Berndt, C., Vogelbacher, C., Jansen, A., Kircher, T., Falkenberg, I., Lambert, M., Kraft, V., Leicht, G., Mulert, C., Fallgatter, A. J., Ethofer, T., Rau, A., Leopold, K., … Pfennig, A. (2023). Prediction of estimated risk for bipolar disorder using machine learning and structural MRI features. Psychological Medicine. https://doi.org/10.1017/s0033291723001319

Müller CP, Schumann G, Rehm J, Kornhuber J, Lenz B. Self-management with alcohol over lifespan: psychological mechanisms, neurobiological underpinnings, and risk assessment. Mol Psychiatry. 2023 Apr 28. [Epub ahead of print]

Musial, M. P. M., Beck, A., Rosenthal, A., Charlet, K., Bach, P., Kiefer, F., Vollstädt-Klein, S., Walter, H., Heinz, A., & Rothkirch, M. (2023). Reward Processing in Alcohol-Dependent Patients and First-Degree Relatives: Functional Brain Activity During Anticipation of Monetary Gains and Losses. Biological Psychiatry, 93(6). https://doi.org/10.1016/j.biopsych.2022.05.024

Nakovics H, Hoffmann S, Koopmann A, Bach P, Abel M, Sommer WH, Kiefer F, Weinland C, von Zimmermann C, Siegmann EM, Kornhuber J, Mühle C, Schneider U, Toto S, Hillemacher T, Frieling H, Bleich S, Eberlein CK, Lenz B. Psychometric properties of the German Penn Alcohol Craving Scale. Alcohol Alcohol. 2023 Jul 26. [Epub ahead of print]

Navarri, X., Vosberg, D. E., Shin, J., Richer, L., Leonard, G., Pike, G. B., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Martinot, M. L. P., Artiges, E., Nees, F., … Paus, T. (2023). A biologically informed polygenic score of neuronal plasticity moderates the association between cognitive aptitudes and cortical thickness in adolescents. Developmental Cognitive Neuroscience, 60. https://doi.org/10.1016/j.dcn.2023.101232

Nickel, S., Endrass, T., & Dieterich, R. (2023). Immediate and lasting effects of different regulation of craving strategies on cue‐induced craving and the late positive potential in smokers. Addiction Biology, 28(8). https://doi.org/10.1111/adb.13315

Opitz, A., Petasch, M. S., Klappauf, R., Kirschgens, J., Hinz, J., Dittmann, L., Dathe, A. S., Quednow, B. B., Beste, C., & Stock, A. K. (2023). Does chronic use of amphetamine-type stimulants impair interference control? – A meta-analysis. In Neuroscience and Biobehavioral Reviews (Vol. 146). https://doi.org/10.1016/j.neubiorev.2022.105020

Pelz P, Genauck A, Lorenz RC, Wüstenberg T, Wackerhagen C, Charlet K, Gleich T, Geisel O, Heinz A, Müller CA, Beck A (2023) Effects of baclofen on insular gain anticipation in alcohol-dependent patients - a randomized, placebo-controlled, pharmaco-fMRI pilot trial.Psychopharmacology (Berl) 240(1):171-183. doi: 10.1007/s00213-022-06291-6

Pérez-Cervera, L., De Santis, S., Marcos, E. et al. Alcohol-induced damage to the fimbria/fornix reduces hippocampal-prefrontal cortex connection during early abstinence. acta neuropathol commun 11, 101 (2023). https://doi.org/10.1186/s40478-023-01597-8

Poisel E, Zillich L, Streit F, Frank J, Friske MM, Foo JC, Mechawar N, Turecki G, Hansson AC, Nothen MM, Rietschel M, Spanagel R, Witt SH. DNA methylation in cocaine use disorder-An epigenome-wide approach in the human prefrontal cortex. Front Psychiatry 14, 1075250 (2023).

Rosenthal A, Chen K, Beck A, Romanczuk-Seiferth N. Modifying Pavlovian-to-instrumental transfer by approach avoidance training in healthy subjects: a proof of concept study. Sci Rep. 2023 Jun 21;13(1):10074. doi: 10.1038/s41598-023-37083-3.

Rosenthal, A., Garbusow, M., Romanczuk-Seiferth, N., & Beck, A. (2023). Effects of a brief mindfulness meditation practice on Pavlovian-to-instrumental transfer in alcohol use disorder – a pilot study. Frontiers in Psychiatry, 14. https://doi.org/10.3389/fpsyt.2023.1134458

Ruiz-España, S., Ortiz-Ramón, R., Pérez-Ramírez, Ú., Díaz-Parra, A., Ciccocioppo, R., Bach, P., Vollstädt-Klein, S., Kiefer, F., Sommer, W. H., Canals, S., & Moratal, D. (2023). MRI texture-based radiomics analysis for the identification of altered functional networks in alcoholic patients and animal models. Computerized Medical Imaging and Graphics, 104. https://doi.org/10.1016/j.compmedimag.2023.102187

Spitta G, Garbusow M, Buchert R, Heinz A. Dopamine and Alcohol: A Review of in vivo PET and SPECT Studies.
Neuropsychobiology 2023; (82(6):319-345.)

Stepanous, J., Munford, L., Qualter, P., Banaschewski, T., Nees, F., Elliott, R., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Martinot, M. L. P., Artiges, E., Orfanos, D. P., Paus, T., … Schumann, G. (2023). Social environment and brain structure in adolescent mental health: A cross-sectional structural equation modelling study using IMAGEN data. PLoS ONE, 18(1 January). https://doi.org/10.1371/journal.pone.0280062

Stepanous, J., Munford, L., Qualter, P., Nees, F., Elliott, R., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Brühl, R., Martinot, J. L., Martinot, M. L. P., Artiges, E., Orfanos, D. P., Paus, T., … Schumann, G. (2023). Longitudinal Associations between Peer and Family Relationships, Emotional Symptoms, and Regional Brain Volume across Adolescence. Journal of Youth and Adolescence, 52(4). https://doi.org/10.1007/s10964-023-01740-7

Stock, A. K., Wendiggensen, P., Ghin, F., & Beste, C. (2023). Alcohol-induced deficits in reactive control of response selection and inhibition are counteracted by a seemingly paradox increase in proactive control. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-28012-5

Stock, A.-K.; Werner, A.; Kuntke, P.; Petasch, M.-S.; Bensmann, W.; Zink, N.; Koyun, A.H.; Quednow, B.B.; Beste, C. Gamma-Aminobutyric Acid and Glutamate Concentrations in the Striatum and Anterior Cingulate Cortex Not Found to Be Associated with Cognitive Flexibility. Brain Sci. 2023, 13, 1192. https://doi.org/10.3390/brainsci13081192

Sun, Y., Jia, T., Barker, E. D., Chen, D., Zhang, Z., Xu, J., Chang, S., Zhou, G., Liu, Y., Tay, N., Luo, Q., Chang, X., Banaschewski, T., Bokde, A. L. W., Flor, H., Grigis, A., Garavan, H., Heinz, A., Martinot, J. L., … Desrivières, S. (2023). Associations of DNA Methylation With Behavioral Problems, Gray Matter Volumes, and Negative Life Events Across Adolescence: Evidence From the Longitudinal IMAGEN Study. Biological Psychiatry, 93(4). https://doi.org/10.1016/j.biopsych.2022.06.012

Takacs, A., & Beste, C. (2023). A neurophysiological perspective on the integration between incidental learning and cognitive control. Communications Biology, 6(1). https://doi.org/10.1038/s42003-023-04692-7

Tan H, Gerchen MF, Bach P, Lee AM, Hummel O, Sommer W, Kirsch P, Kiefer F, Vollstädt-Klein S (2023) Decoding fMRI alcohol cue reactivity and its association with drinking behaviour. BMJ Ment Health 26(1):e300639. doi: 10.1136/bmjment-2022-300639.

Tan H, Hubertus S, Thomas S, Lee AM, Gerhardt S, Gerchen MF, Sommer WH, Kiefer F, Schad L, Vollstädt-Klein S (2023) Association between iron accumulation in the dorsal striatum and compulsive drinking in alcohol use disorder. Psychopharmacology (Berl) 240(2):249-257. doi: 10.1007/s00213-022-06301-7.

 

Thome J, Pinger M, Durstewitz D, Sommer WH, Kirsch P, Koppe G (2023) Model-based experimental manipulation of probabilistic behavior in interpretable behavioral latent variable models. Front Neurosci 16:1077735. doi: 10.3389/fnins.2022.1077735.

von Zimmermann C, Hübner M, Mühle C, Müller CP, Weinland C, Kornhuber J, Lenz B. Masculine depression and its problem behaviors: use alcohol and drugs, work hard, and avoid psychiatry!. Eur Arch Psychiatry Clin Neurosci. 2023 Feb 28. [Epub ahead of print]

Vulser, H., Lemaître, H. S., Guldner, S., Bezivin-Frère, P., Löffler, M., Sarvasmaa, A. S., Massicotte-Marquez, J., Artiges, E., Paillère Martinot, M. L., Filippi, I., Miranda, R., Stringaris, A., van Noort, B. M., Penttilä, J., Grimmer, Y., Becker, A., Banaschewski, T., Bokde, A. L. W., Desrivières, S., … Nees, F. (2023). Chronotype, Longitudinal Volumetric Brain Variations Throughout Adolescence, and Depressive Symptom Development. Journal of the American Academy of Child and Adolescent Psychiatry, 62(1). https://doi.org/10.1016/j.jaac.2022.06.003

Wenger, L.P., Hamm, O., Mühle, C. et al. Alcohol does not influence trust in others or oxytocin, but increases positive affect and risk-taking: a randomized, controlled, within-subject trial. Eur Arch Psychiatry Clin Neurosci (2023). https://doi.org/10.1007/s00406-023-01676-w

Zech H, Waltmann M, Lee Y, Reichert M, Bedder RL, Rutledge RB, Deeken F, Wenzel J, Wedemeyer F, Aguilera A, Aslan A, Bach P, Bahr NS, Ebrahimi C, Fischbach PC, Ganz MG, Garbusow M, Großkopf CM, Heigert M, Hentschel A, Belanger M, Karl D, Pelz P, Pinger MP, Riemerschmid C, Rosenthal A, Steffen J, Strehle J, Weiss F, Wieder G, Wieland A, Zaiser JZ, Zimmermann S, Liu S, Goschke T, Walter H, Tost H, Lenz B, Andoh JA, Ebner-Priemer U, Rapp MA, Heinz A, Dolan R, Smolka MN, Deserno L, ReCoDe-Consortium . Measuring self-regulation in everyday life: Reliability and validity of smartphone-based experiments in alcohol use disorder. Behav Res Methods. 2022 Dec 12. [Epub ahead of print]

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